In Modern age all the matters and elements become digital and medical and healthcare system is not an exception. Advanced ICT and Computing in Healthcare results Digital Healthcare Systems for th advancement of healthcare and allied sector and industry. Initially only basic Information Technologies viz. Database, Networks, Multimedia, Networking, Software, etc. are considered as valuable and impactful, however in recent past other emerging technologies. Latest technological applications in healthcare brings several advantages and benefits of healthcare viz. speed, transparency, sharing, effective documentation, effective operations, instant and collaborated laboratory systems, etc. India is moving towards a digital economy supported by e-governance, m-governance, etc. and Digital Healthcare Systems may avail wider benefits with such additional benefits. Though there are ample advantages of Advanced ICT in Healthcare but though there are issues, challenges, and concern in Digital Healthcare viz. technological implementation and management, human resources, government norms and regulations, Data Susceptibility, Implementation loopholes, Cyber Security issues, etc. This work is a comprehensive one in regard to Digital Healthcare Systems including foundation, basic & emerging technologies, and initiative in India, challenges and issues, including possible solutions.